Molecules (Feb 2016)

Multicomponent Synthesis and Evaluation of New 1,2,3-Triazole Derivatives of Dihydropyrimidinones as Acidic Corrosion Inhibitors for Steel

  • Rodrigo González-Olvera,
  • Viridiana Román-Rodríguez,
  • Guillermo E. Negrón-Silva,
  • Araceli Espinoza-Vázquez,
  • Francisco Javier Rodríguez-Gómez,
  • Rosa Santillan

DOI
https://doi.org/10.3390/molecules21020250
Journal volume & issue
Vol. 21, no. 2
p. 250

Abstract

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An efficient one-pot synthesis of 1,2,3-triazole derivatives of dihydropyrimidinones has been developed using two multicomponent reactions. The aldehyde-1,2,3-triazoles were obtained in good yields from in situ-generated organic azides and O-propargylbenzaldehyde. The target heterocycles were synthesized through the Biginelli reaction in which the aldehyde-1,2,3-triazoles reacted with ethyl acetoacetate and urea in the presence of Ce(OTf)3 as the catalyst. The corrosion inhibition of steel grade API 5 L X52 in 1 M HCl by the synthesized compounds was investigated using the electrochemical impedance spectroscopy technique. The measurements revealed that these heterocycles are promising candidates to inhibit acidic corrosion of steel.

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