A microfluidic optimal experimental design platform for forward design of cell-free genetic networks

Bob van Sluijs; Roel J. M. Maas; Ardjan J. van der Linden; Tom F. A. de Greef; Wilhelm T. S. Huck

doi:10.1038/s41467-022-31306-3

Nature Communications (Jun 2022)

A microfluidic optimal experimental design platform for forward design of cell-free genetic networks

Bob van Sluijs,
Roel J. M. Maas,
Ardjan J. van der Linden,
Tom F. A. de Greef,
Wilhelm T. S. Huck

Affiliations

Bob van Sluijs: Institute for Molecules and Materials, Radboud University
Roel J. M. Maas: Institute for Molecules and Materials, Radboud University
Ardjan J. van der Linden: Laboratory of Chemical Biology, Department of Biomedical Engineering, Eindhoven University of Technology
Tom F. A. de Greef: Institute for Molecules and Materials, Radboud University
Wilhelm T. S. Huck: Institute for Molecules and Materials, Radboud University

DOI: https://doi.org/10.1038/s41467-022-31306-3
Journal volume & issue: Vol. 13, no. 1
pp. 1 – 11

Abstract

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Characterization of cell-free genetic networks is inherently difficult. Here the authors use optimal experimental design and microfluidics to improve characterization, demonstrating modularity and predictability of parts in applied test cases.

Published in Nature Communications

ISSN: 2041-1723 (Online)
Publisher: Nature Portfolio
Country of publisher: United Kingdom
LCC subjects: Science
Website: https://www.nature.com/ncomms/

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