Downregulation of lncRNA FGF12-AS2 suppresses the tumorigenesis of NSCLC via sponging miR-188-3p

Zhou Lili; Xing Chen; Zhou Dongxia; Yang Rong; Cai Maohuai

doi:10.1515/med-2020-0219

Open Medicine (Oct 2020)

Downregulation of lncRNA FGF12-AS2 suppresses the tumorigenesis of NSCLC via sponging miR-188-3p

Zhou Lili,
Xing Chen,
Zhou Dongxia,
Yang Rong,
Cai Maohuai

Affiliations

Zhou Lili: Department of Oncology, Yancheng Second People’s Hospital, No. 135 Kaifang Avenue, Yancheng 224003, Jiangsu, China
Xing Chen: Department of Oncology, Yancheng Second People’s Hospital, No. 135 Kaifang Avenue, Yancheng 224003, Jiangsu, China
Zhou Dongxia: Department of Oncology, Yancheng Second People’s Hospital, No. 135 Kaifang Avenue, Yancheng 224003, Jiangsu, China
Yang Rong: Department of Oncology, Yancheng Second People’s Hospital, No. 135 Kaifang Avenue, Yancheng 224003, Jiangsu, China
Cai Maohuai: Department of Oncology, Yancheng Second People’s Hospital, No. 135 Kaifang Avenue, Yancheng 224003, Jiangsu, China

DOI: https://doi.org/10.1515/med-2020-0219
Journal volume & issue: Vol. 15, no. 1
pp. 986 – 996

Abstract

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Non-small-cell lung carcinoma (NSCLC) seriously threatens the health of human beings. Aberrant expression of lncRNAs has been confirmed to be related with the progression of multiple malignant tumors, including NSCLC. LncRNA FGF12-AS2 has been considered to be upregulated in NSCLC. However, the mechanism by which FGF12-AS2 promotes the tumorigenesis of NSCLC remains elusive.

Published in Open Medicine

ISSN: 2391-5463 (Online)
Publisher: De Gruyter
Country of publisher: Poland
LCC subjects: Medicine
Website: https://www.degruyter.com/journal/key/med/html

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