Communications Medicine (Nov 2022)

Vaccines against the original strain of SARS-CoV-2 provide T cell memory to the B.1.1.529 variant

  • Charlyn Dörnte,
  • Verena Traska,
  • Nicole Jansen,
  • Julia Kostyra,
  • Herrad Baurmann,
  • Gereon Lauer,
  • Yi-Ju Huang,
  • Sven Kramer,
  • Olaf Brauns,
  • Holger Winkels,
  • Jürgen Schmitz,
  • Christian Dose,
  • Anne Richter,
  • Marc Schuster

DOI
https://doi.org/10.1038/s43856-022-00203-7
Journal volume & issue
Vol. 2, no. 1
pp. 1 – 6

Abstract

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Dörnte et al. analyze whether T cell memory towards the B.1.1.529 spike protein of SARS-CoV-2 is retained in individuals vaccinated against the original Wuhan strain of SARS-CoV-2. CD4 and CD8 responses are slightly reduced compared to responses to the original spike protein.