Nature Communications (Feb 2020)
Gut microbiota mediates intermittent-fasting alleviation of diabetes-induced cognitive impairment
- Zhigang Liu,
- Xiaoshuang Dai,
- Hongbo Zhang,
- Renjie Shi,
- Yan Hui,
- Xin Jin,
- Wentong Zhang,
- Luanfeng Wang,
- Qianxu Wang,
- Danna Wang,
- Jia Wang,
- Xintong Tan,
- Bo Ren,
- Xiaoning Liu,
- Tong Zhao,
- Jiamin Wang,
- Junru Pan,
- Tian Yuan,
- Chuanqi Chu,
- Lei Lan,
- Fei Yin,
- Enrique Cadenas,
- Lin Shi,
- Shancen Zhao,
- Xuebo Liu
Affiliations
- Zhigang Liu
- College of Food Science and Engineering, Northwest A&F University
- Xiaoshuang Dai
- BGI Institute of Applied Agriculture, BGI-Shenzhen
- Hongbo Zhang
- College of Food Science and Engineering, Northwest A&F University
- Renjie Shi
- College of Food Science and Engineering, Northwest A&F University
- Yan Hui
- BGI Institute of Applied Agriculture, BGI-Shenzhen
- Xin Jin
- BGI Institute of Applied Agriculture, BGI-Shenzhen
- Wentong Zhang
- College of Food Science and Engineering, Northwest A&F University
- Luanfeng Wang
- College of Food Science and Engineering, Northwest A&F University
- Qianxu Wang
- College of Food Science and Engineering, Northwest A&F University
- Danna Wang
- College of Food Science and Engineering, Northwest A&F University
- Jia Wang
- College of Food Science and Engineering, Northwest A&F University
- Xintong Tan
- College of Food Science and Engineering, Northwest A&F University
- Bo Ren
- College of Food Science and Engineering, Northwest A&F University
- Xiaoning Liu
- College of Food Science and Engineering, Northwest A&F University
- Tong Zhao
- College of Food Science and Engineering, Northwest A&F University
- Jiamin Wang
- College of Food Science and Engineering, Northwest A&F University
- Junru Pan
- College of Food Science and Engineering, Northwest A&F University
- Tian Yuan
- College of Food Science and Engineering, Northwest A&F University
- Chuanqi Chu
- College of Food Science and Engineering, Northwest A&F University
- Lei Lan
- BGI Institute of Applied Agriculture, BGI-Shenzhen
- Fei Yin
- Center for Innovation in Brain Science and Department of Pharmacology, University of Arizona
- Enrique Cadenas
- Pharmacology and Pharmaceutical Sciences, School of Pharmacy, University of Southern California
- Lin Shi
- Division Food and Nutrition Science, Department of Biology and Biological Engineering, Chalmers University of Technology
- Shancen Zhao
- BGI Institute of Applied Agriculture, BGI-Shenzhen
- Xuebo Liu
- College of Food Science and Engineering, Northwest A&F University
- DOI
- https://doi.org/10.1038/s41467-020-14676-4
- Journal volume & issue
-
Vol. 11,
no. 1
pp. 1 – 14
Abstract
Intermittent fasting (IF) has been shown beneficial in reducing metabolic diseases. Here, using a multi-omics approach in a T2D mouse model, the authors report that IF alters the composition of the gut microbiota and improves metabolic phenotypes that correlate with cognitive behavior.
