Nature Communications (Oct 2019)
Unique structure and function of viral rhodopsins
- Dmitry Bratanov,
- Kirill Kovalev,
- Jan-Philipp Machtens,
- Roman Astashkin,
- Igor Chizhov,
- Dmytro Soloviov,
- Dmytro Volkov,
- Vitaly Polovinkin,
- Dmitrii Zabelskii,
- Thomas Mager,
- Ivan Gushchin,
- Tatyana Rokitskaya,
- Yuri Antonenko,
- Alexey Alekseev,
- Vitaly Shevchenko,
- Natalya Yutin,
- Riccardo Rosselli,
- Christian Baeken,
- Valentin Borshchevskiy,
- Gleb Bourenkov,
- Alexander Popov,
- Taras Balandin,
- Georg Büldt,
- Dietmar J. Manstein,
- Francisco Rodriguez-Valera,
- Christoph Fahlke,
- Ernst Bamberg,
- Eugene Koonin,
- Valentin Gordeliy
Affiliations
- Dmitry Bratanov
- Institute of Complex Systems (ICS), ICS-6: Structural Biochemistry, Forschungszentrum Jülich
- Kirill Kovalev
- Institute of Complex Systems (ICS), ICS-6: Structural Biochemistry, Forschungszentrum Jülich
- Jan-Philipp Machtens
- Institute of Complex Systems (ICS), ICS-4: Zelluläre Biophysik, Forschungszentrum Jülich
- Roman Astashkin
- Institut de Biologie Structurale J.-P. Ebel, Université Grenoble Alpes-CEA-CNRS
- Igor Chizhov
- Institute for Biophysical Chemistry, Hannover Medical School
- Dmytro Soloviov
- Moscow Institute of Physics and Technology
- Dmytro Volkov
- Institute of Complex Systems (ICS), ICS-6: Structural Biochemistry, Forschungszentrum Jülich
- Vitaly Polovinkin
- Institute of Complex Systems (ICS), ICS-6: Structural Biochemistry, Forschungszentrum Jülich
- Dmitrii Zabelskii
- Institute of Complex Systems (ICS), ICS-6: Structural Biochemistry, Forschungszentrum Jülich
- Thomas Mager
- Max Planck Institute of Biophysics
- Ivan Gushchin
- Moscow Institute of Physics and Technology
- Tatyana Rokitskaya
- Belozersky Institute of Physico-Chemical Biology, Lomonosov Moscow State University
- Yuri Antonenko
- Belozersky Institute of Physico-Chemical Biology, Lomonosov Moscow State University
- Alexey Alekseev
- Institute of Complex Systems (ICS), ICS-6: Structural Biochemistry, Forschungszentrum Jülich
- Vitaly Shevchenko
- Institute of Complex Systems (ICS), ICS-6: Structural Biochemistry, Forschungszentrum Jülich
- Natalya Yutin
- National Center for Biotechnology Information, National Library of Medicine, National Institutes of Health
- Riccardo Rosselli
- Evolutionary Genomics Group, Departamento de Producción Vegetal y Microbiología, Universidad Miguel Hernández
- Christian Baeken
- Institute of Complex Systems (ICS), ICS-6: Structural Biochemistry, Forschungszentrum Jülich
- Valentin Borshchevskiy
- Institute of Complex Systems (ICS), ICS-6: Structural Biochemistry, Forschungszentrum Jülich
- Gleb Bourenkov
- European Molecular Biology Laboratory, Hamburg unit c/o DESY
- Alexander Popov
- European Synchrotron Radiation Facility
- Taras Balandin
- Institute of Complex Systems (ICS), ICS-6: Structural Biochemistry, Forschungszentrum Jülich
- Georg Büldt
- Moscow Institute of Physics and Technology
- Dietmar J. Manstein
- Institute for Biophysical Chemistry, Hannover Medical School
- Francisco Rodriguez-Valera
- Evolutionary Genomics Group, Departamento de Producción Vegetal y Microbiología, Universidad Miguel Hernández
- Christoph Fahlke
- Moscow Institute of Physics and Technology
- Ernst Bamberg
- Moscow Institute of Physics and Technology
- Eugene Koonin
- National Center for Biotechnology Information, National Library of Medicine, National Institutes of Health
- Valentin Gordeliy
- Institute of Complex Systems (ICS), ICS-6: Structural Biochemistry, Forschungszentrum Jülich
- DOI
- https://doi.org/10.1038/s41467-019-12718-0
- Journal volume & issue
-
Vol. 10,
no. 1
pp. 1 – 13
Abstract
Rhodopsin genes have been identified in some large double-stranded DNA viruses, but the structure and functions of viral rhodopsins remain unknown. Here authors present crystal structure and characterization of an Organic Lake Phycodnavirus rhodopsin II (OLPVRII) which forms a pentamer and is a weak proton pump.
