Journal for ImmunoTherapy of Cancer (Oct 2020)
Defining best practices for tissue procurement in immuno-oncology clinical trials: consensus statement from the Society for Immunotherapy of Cancer Surgery Committee
- Lisa H Butterfield,
- Howard L Kaufman,
- Steven A Rosenberg,
- Simon Turcotte,
- Robert L Ferris,
- Craig L Slingluff,
- David Byrd,
- Jyothi Sethuraman,
- Brian Gastman,
- Michael Lim,
- Michael T Lotze,
- Mokenge Malafa,
- Adekunle Odunsi,
- Fumito Ito,
- Genevieve Boland,
- Pranav Murthy,
- Adam Berger,
- Haider Mahdi,
- Piyush K Agarwal,
- Stephen Broderick,
- Peter E Fecci,
- Yuman Fong,
- Stephanie L Goff,
- Matthew M Grabowski,
- Carol D Morris,
- Rogerio I Neves,
- Sara I Pai,
- Sangeetha Prabhakaran,
- Ragheed Saoud,
- Joseph Skitzki,
- Vernon K Sondak,
- John B Sunwoo,
- Cecilia CS Yeung
Affiliations
- Lisa H Butterfield
- 7Merck Research Laboratories, South San Francisco, CA, USA
- Howard L Kaufman
- Department of Surgery, Massachusetts General Hospital and Harvard Medical School, Boston, Massachusetts, USA
- Steven A Rosenberg
- Surgery Branch, Center for Cancer Research, National Cancer Institute, Bethesda, Maryland, USA
- Simon Turcotte
- 4Université de Montréal, Montreal, QC, Canada
- Robert L Ferris
- Hillman Cancer Center, University of Pittsburgh Medical Center Health System, Pittsburgh, Pennsylvania, USA
- Craig L Slingluff
- 4 Department of Surgery, University of Virginia, Charlottesville, Virginia, USA
- David Byrd
- Aff138 grid.34477.330000000122986657University of Washington Seattle WA USA
- Jyothi Sethuraman
- Aff174 Lion Biotechnologies, Inc. Tampa FL USA
- Brian Gastman
- Department of Plastic Surgery, Cleveland Clinic, Cleveland, Ohio, USA
- Michael Lim
- Department of Neurosurgery, Stanford University, Stanford, California, USA
- Michael T Lotze
- UPMC Hillman Cancer Center and University of Pittsburgh, Pittsburgh, Pennsylvania, USA
- Mokenge Malafa
- Aff2 grid.468198.a0000000098915233Gastrointestinal Oncology Program, H Lee Moffitt Cancer Center and Research Institute Tampa FL USA
- Adekunle Odunsi
- 17 Department of Gynecologic Oncology, Roswell Park Cancer Institute, Buffalo, New York, USA
- Fumito Ito
- Center for Immunotherapy, Roswell Park Comprehensive Cancer Center, Buffalo, New York, USA
- Genevieve Boland
- Department of Surgical Oncology, Massachusetts General Hospital, Harvard Medical School, Boston, Massachusetts, USA
- Pranav Murthy
- 1University of Pittsburgh, Pittsburgh, PA, USA
- Adam Berger
- Rutgers Cancer Institute of New Jersey, New Brunswick, New Jersey, USA
- Haider Mahdi
- 18 Department of Obstetrics, Gynecology & Reproductive Sciences, University of Pittsburgh Medical Center, Pittsburgh, Pennsylvania, USA
- Piyush K Agarwal
- 2 Department of Surgery, University of Chicago, Chicago, Illinois, USA
- Stephen Broderick
- 5 Oncology, Johns Hopkins Medicine Sidney Kimmel Comprehensive Cancer Center, Baltimore, Maryland, USA
- Peter E Fecci
- 3Duke Cancer Institute, Durham, NC, USA
- Yuman Fong
- 1City of Hope, Duarte, CA, USA
- Stephanie L Goff
- Surgery Branch, Center for Cancer Research, National Cancer Institute, Bethesda, Maryland, USA
- Matthew M Grabowski
- 14 Department of Neurosurgery, Duke Center for Brain and Spine Metastasis, Durham, North Carolina, USA
- Carol D Morris
- Division of Orthopaedic Oncology, Department of Orthopaedic Surgery, Johns Hopkins University, Baltimore, Maryland, USA
- Rogerio I Neves
- 22 Department of Surgery, Penn State Cancer Institute, Hershey, Pennsylvania, USA
- Sara I Pai
- 10 Department of Surgical Oncology, Massachusetts General Hospital, Boston, Massachusetts, USA
- Sangeetha Prabhakaran
- 24 Division of Surgical Oncology, Department of Surgery, UNM Comprehensive Cancer Center, University of New Mexico, Albuquerque, New Mexico, USA
- Ragheed Saoud
- 26 Department of Surgery, University of Chicago Hospitals, Chicago, Illinois, United States
- Joseph Skitzki
- 28 Departments of Surgical Oncology and Immunology, Roswell Park Comprehensive Cancer Center, Buffalo, New York, USA
- Vernon K Sondak
- Department of Cutaneous Oncology, Moffitt Cancer Center, Tampa, Florida, USA
- John B Sunwoo
- 31 Department of Otolaryngology, Stanford University School of Medicine, Stanford, California, USA
- Cecilia CS Yeung
- 33 Department of Pathology, Fred Hutchinson Cancer Research Center, Seattle, Washington, USA
- DOI
- https://doi.org/10.1136/jitc-2020-001583
- Journal volume & issue
-
Vol. 8,
no. 2
Abstract
Immunotherapy is now a cornerstone for cancer treatment, and much attention has been placed on the identification of prognostic and predictive biomarkers. The success of biomarker development is dependent on accurate and timely collection of biospecimens and high-quality processing, storage and shipping. Tumors are also increasingly used as source material for the generation of therapeutic T cells. There have been few guidelines or consensus statements on how to optimally collect and manage biospecimens and source material being used for immunotherapy and related research. The Society for Immunotherapy of Cancer Surgery Committee has brought together surgical experts from multiple subspecialty disciplines to identify best practices and to provide consensus on how best to access and manage specific tissues for immuno-oncology treatments and clinical investigation. In addition, the committee recommends early integration of surgeons and other interventional physicians with expertise in biospecimen collection, especially in clinical trials, to optimize the quality of tissue and the validity of correlative clinical studies in cancer immunotherapy.
