Retrovirology (Feb 2007)

Methylation: a regulator of HIV-1 replication?

  • Jeang Kuan-Teh,
  • Yedavalli Venkat RK

DOI
https://doi.org/10.1186/1742-4690-4-9
Journal volume & issue
Vol. 4, no. 1
p. 9

Abstract

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Abstract Recent characterizations of methyl transferases as regulators of cellular processes have spurred investigations into how methylation events might influence the HIV-1 life cycle. Emerging evidence suggests that protein-methylation can positively and negatively regulate HIV-1 replication. How DNA- and RNA- methylation might impact HIV-1 is also discussed.