Substrate Dynamics Contribute to Enzymatic Specificity in Human and Bacterial Methionine Adenosyltransferases

• Madhuri Gade,
• Li Lynn Tan,
• Adam M. Damry,
• Mahakaran Sandhu,
• Joseph S. Brock,
• Andie Delaney,
• Alejandro Villar-Briones,
• Colin J. Jackson,
• Paola Laurino

Affiliations

Madhuri Gade

Protein Engineering and Evolution Unit, Okinawa Institute of Science and Technology Graduate University, Onna, Okinawa, Japan

Li Lynn Tan

Research School of Chemistry, Australian National University, Canberra, Australia

Adam M. Damry

Research School of Chemistry, Australian National University, Canberra, Australia

Mahakaran Sandhu

Research School of Chemistry, Australian National University, Canberra, Australia

Joseph S. Brock

Research School of Biology, Australian National University, Canberra, Australia

Andie Delaney

Research School of Chemistry, Australian National University, Canberra, Australia

Alejandro Villar-Briones

Protein Engineering and Evolution Unit, Okinawa Institute of Science and Technology Graduate University, Onna, Okinawa, Japan

Colin J. Jackson

Research School of Chemistry, Australian National University, Canberra, Australia

Paola Laurino

Protein Engineering and Evolution Unit, Okinawa Institute of Science and Technology Graduate University, Onna, Okinawa, Japan