Building up a Continuous Flow Platform as an Enabler to the Preparation of Intermediates on Kilogram Scale

Abstract

The following outlook describes the strategy we followed at Syngenta R&D to build and develop an effective flow chemistry platform which could fit a precise business purpose. In this account, we give insight into specific chemistry challenges encountered and addressed using continuous flow chemistry. The conclusions of the outlook outline the future of our strategy with a perspective on the technology within our business.

Keywords

• Bromination
• Continuous flow chemistry
• Hazardous chemistry
• Nitration
• Scale-up