Study of Primary Chest Wall Tumours in a Tertiary Care Hospital

Abstract

Introduction: Primary chest wall tumours are infrequent, but wide variety of tumours arise within the chest wall and comprise 7 to 8% of all intrinsic bone tumours. Tumours that arise from the chest wall include from the bony structures (sternum, scapula, ribs) or from the adjacent soft tissue. Aim: To analyse the clinical details, imaging reports, histological findings of the tumour and its correlation with Immunohistochemistry (IHC). Materials and Methods: A prospective study was conducted from December 2017 to December 2019 at Institute of Post Graduate Medical Education and Research, Kolkata, West Bengal (India). Sixteen cases were evaluated in terms of clinical history, imaging and histological findings, the treatment provided. GraphPad InStat 3 was used to analyse the results. Results: Of the 16 cases of chest wall tumours, 10 (62.5%) were malignant and 6 (37.5%) were benign. Patients with benign and malignant tumours had overlapped age ranges considerably, similar to the ranges of duration of symptoms. The sex distribution did not reveal any marked predilection for males (eight males, eight females). All the patients underwent treatment and are under follow-up. Conclusion: Chest wall neoplasms are group of heterogeneous lesions with varied pathology. Any tumour arising from chest wall should be inspected properly to ascertain the origin of the tumour for a definitive diagnosis. Clinical and imaging correlation along with histopathology and IHC aids in proper diagnosis.

Keywords

• benign
• histopathology
• immunohistochemistry
• malignant