578 Anti-PD-1 therapy alters the generation and durability of de novo responses to vaccination in humans

• Michael Manos,
• Arlene Sharpe,
• F Stephen Hodi,
• Joanna Baginska,
• Elizabeth I Buchbinder,
• Marta Holovatska,
• Kelly P Burke,
• Taras M Chicz,
• Julia Huezo,
• Duck Kyun Yoo,
• Fnu Keerti,
• Caihong Bi,
• Ryan McNamara,
• Duane Wesemann

Affiliations

Michael Manos

1Dana-Farber Cancer Institute, Boston, MA, USA

Arlene Sharpe

Aff4 grid.38142.3c000000041936754XHarvard Medical School Boston MA USA

F Stephen Hodi

2Dana-Farber Cancer Institute, Boston, MA, USA

Joanna Baginska

Dana-Farber Cancer Institute, Boston, MA, USA

Elizabeth I Buchbinder

1Dana-Farber Cancer Institute, Boston, MA, USA

Marta Holovatska

1Dana-Farber Cancer Institute, Boston, MA, USA

Kelly P Burke

1Dana-Farber Cancer Institute, Boston, MA, USA

Taras M Chicz

3Ragon Institute of MGH, MIT, and Harvard, Cambridge, MA, USA

Julia Huezo

1Dana-Farber Cancer Institute, Boston, MA, USA

Duck Kyun Yoo

4Brigham and Women’s Hospital, Boston, MA, USA

Fnu Keerti

4Brigham and Women’s Hospital, Boston, MA, USA

Caihong Bi

4Brigham and Women’s Hospital, Boston, MA, USA

Ryan McNamara

3Ragon Institute of MGH, MIT, and Harvard, Cambridge, MA, USA

Duane Wesemann

3Ragon Institute of MGH, MIT, and Harvard, Cambridge, MA, USA