Analysis of retinopathy of prematurity screening between 2009 and 2013 in Tianjin, China

Abstract

AIM: To analyze the findings of retinopathy of prematurity(ROP)exam in Tianjin, and study the impact of pulmonary surfactant Curosurf and nasal continuous positive airway pressure(NCPAP)in ROP.METHODS: A multicenter retrospective review. Totally 2894 preterm infants(1592 males, 1302 females)from several hospitals in Tianjin were screened from January 2009 to December 2013. Demographic information, ophthalmic outcomes and possible systemic risk factors were recorded. Gestation age, birth weight, oxygen supplementation, Curosurf and NCPAP were used to estimate risk factors for ROP.RESULTS: ROP was found in 448 eyes of 224 patients(7.7%). Among which, severe ROP developed in 98 eyes of 49 patients(21.9%). There was significant statistical difference in respiratory distress syndrome(RDS), NCPAP, and Curosurf usage between control and ROP groups(PCONCLUSION: Low birth weight, young gestational age and oxygen supplementation are associated with ROP. The use of Curosurf and NCPAP may be the factor that reduces the occurrence of ROP.

Keywords

• retinopathy of prematurity
• incidence
• risk factor
• pulmonary surfactant
• nasal continuous positive airway pressure
• nasal continuous positive airway pressure