New Route to 3-Alkylthiazolo[3,2-a]benzimidazole Derivatives

Abstract

3-Alkyl-thiazolo[3,2-a]benzimidazole derivatives are obtained in high yieldsvia the corresponding 4-alkyl-N-3-(2-aminophenyl)-thiazoline-2-thiones which are easilyprepared from 1,2-diaminobenzene, CS2 and halogenoketones. This new route comparesadvantageously with the classical mercaptobenzimidazole routes in term of simplicity,isolated yields and availability of the starting materials.

Keywords

• 2-Methylthiothiazolium salts
• fused heterocycles
• ring closure.