Nature Communications (Nov 2021)

Associations between patterns in comorbid diagnostic trajectories of individuals with schizophrenia and etiological factors

  • Morten Dybdahl Krebs,
  • Gonçalo Espregueira Themudo,
  • Michael Eriksen Benros,
  • Ole Mors,
  • Anders D. Børglum,
  • David Hougaard,
  • Preben Bo Mortensen,
  • Merete Nordentoft,
  • Michael J. Gandal,
  • Chun Chieh Fan,
  • Daniel H. Geschwind,
  • Andrew J. Schork,
  • Thomas Werge,
  • Wesley K. Thompson

DOI
https://doi.org/10.1038/s41467-021-26903-7
Journal volume & issue
Vol. 12, no. 1
pp. 1 – 12

Abstract

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Schizophrenia is a complex disorder where individuals experience different symptoms and outcomes that can be captured by patterns in other diagnoses. Here the authors use computational approaches to summarize these patterns and suggest they are associated with genetic and environmental exposure.