Nature Communications (Jul 2019)
circTP63 functions as a ceRNA to promote lung squamous cell carcinoma progression by upregulating FOXM1
- Zhuoan Cheng,
- Chengtao Yu,
- Shaohua Cui,
- Hui Wang,
- Haojie Jin,
- Cun Wang,
- Botai Li,
- Meilin Qin,
- Chen Yang,
- Jia He,
- Qiaozhu Zuo,
- Siying Wang,
- Jun Liu,
- Weidong Ye,
- Yuanyuan Lv,
- Fangyu Zhao,
- Ming Yao,
- Liyan Jiang,
- Wenxin Qin
Affiliations
- Zhuoan Cheng
- State Key Laboratory of Oncogenes and Related Genes, Shanghai Cancer Institute, Renji Hospital, Shanghai Jiao Tong University School of Biomedical Engineering
- Chengtao Yu
- State Key Laboratory of Oncogenes and Related Genes, Shanghai Cancer Institute, Renji Hospital, Shanghai Jiao Tong University School of Biomedical Engineering
- Shaohua Cui
- Department of Respiratory Medicine, Shanghai Chest Hospital, Shanghai Jiao Tong University
- Hui Wang
- Shanghai Cancer Institute, Renji Hospital, Shanghai Jiao Tong University School of Medicine
- Haojie Jin
- Shanghai Cancer Institute, Renji Hospital, Shanghai Jiao Tong University School of Medicine
- Cun Wang
- Shanghai Cancer Institute, Renji Hospital, Shanghai Jiao Tong University School of Medicine
- Botai Li
- State Key Laboratory of Oncogenes and Related Genes, Shanghai Cancer Institute, Renji Hospital, Shanghai Jiao Tong University School of Biomedical Engineering
- Meilin Qin
- Shanghai Cancer Institute, Renji Hospital, Shanghai Jiao Tong University School of Medicine
- Chen Yang
- Shanghai Medical College of Fudan University
- Jia He
- Shanghai Cancer Institute, Renji Hospital, Shanghai Jiao Tong University School of Medicine
- Qiaozhu Zuo
- Shanghai Cancer Institute, Renji Hospital, Shanghai Jiao Tong University School of Medicine
- Siying Wang
- Shanghai Cancer Institute, Renji Hospital, Shanghai Jiao Tong University School of Medicine
- Jun Liu
- Department of Respiratory Medicine, Shanghai Chest Hospital, Shanghai Jiao Tong University
- Weidong Ye
- Department of General Surgery, Shanghai Jiao Tong University Affiliated Sixth People’s Hospital
- Yuanyuan Lv
- Shanghai Cancer Institute, Renji Hospital, Shanghai Jiao Tong University School of Medicine
- Fangyu Zhao
- Shanghai Cancer Institute, Renji Hospital, Shanghai Jiao Tong University School of Medicine
- Ming Yao
- Shanghai Cancer Institute, Renji Hospital, Shanghai Jiao Tong University School of Medicine
- Liyan Jiang
- Department of Respiratory Medicine, Shanghai Chest Hospital, Shanghai Jiao Tong University
- Wenxin Qin
- State Key Laboratory of Oncogenes and Related Genes, Shanghai Cancer Institute, Renji Hospital, Shanghai Jiao Tong University School of Biomedical Engineering
- DOI
- https://doi.org/10.1038/s41467-019-11162-4
- Journal volume & issue
-
Vol. 10,
no. 1
pp. 1 – 13
Abstract
Circular RNAs are known to regulate cancer. Here, the authors show that the circular RNA circTP63 promotes lung squamous cell carcinoma by competing with endogenous RNA to upregulate FOXM1.
