Application of anakinra in inflammatory dermatoses

Abstract

Interleukin 1(IL-1) is an important cytokine, which is involved in the development of many inflammatory diseases. IL-1 inhibitors have become an effective approach in the treatment of these diseases. Anakinra is the first and the most widely used IL-1 inhibitor on the market. Studies have shown satisfactory efficacy in the treatment of some inflammatory dermatoses. This review mainly summarizes applications of anakinra in adult-onset Still's disease, Schnitzler syndrome, hidradenitis suppurativa, pustular psoriasis, Bechet disease and pyoderma gangrenosum.

Keywords

• il-1
• il-1 inhibitors
• anakinra
• inflammatory skin diseases