Quality of life in patients of corrosive esophageal stricture treated with endoscopic dilatation

Abstract

Abstract Background and Aim Caustic ingestion is associated with long‐term sequelae in the form of esophageal and/or gastric cicatrization requiring endoscopic or surgical intervention. Quality of life (QoL) and disability in patients with caustic‐induced sequelae is less explored. Methods In this prospective study, we included consecutive patients with symptomatic caustic‐induced esophageal stricture undergoing endoscopic dilatation. QoL was measured using the World Health Organization Quality of Life questionnaire (WHOQoL‐BREF). Disability was measured using the World Health Organization Disability Assessment Schedule 2.0 (WHODAS 2.0). Subjective dysphagia score was calculated by Likert scale. Results A total of 42 patients were included in the study; 25 (59.5%) patients were male. Patients had poor WHOQoL‐BREF and WHODAS scores compared to normality data in all domains of the scores among both the genders. A majority (66.7%) of patients had a current psychiatric diagnosis, with the most common being mood disorder (50%) followed by suicidality (45.2%). Males had a higher prevalence of a previous psychiatric diagnosis compared to females, while females had a higher prevalence of suicidality. Dysphagia score had strong correlation with the WHOQoL (r = −0.66; P < 0.01) and WHODAS (r = 0.71; P < 0.01). Conclusion Patients with esophageal stricture due to caustic ingestion on long‐term endoscopic dilatation have poor QoL, high prevalence of psychological morbidity, and disability.

Keywords

• disability
• Patient Health Questionnare‐9 score
• World Health Organization Disability Assessment Schedule score
• WHOQoL‐BREF score