Bangladesh Journal of Pharmacology (Oct 2017)

Hypoglycemic effect of Camellia chrysantha extract on type 2 diabetic mice model

  • Lai Wang,
  • Debmalya Roy,
  • Sen Sen Lin,
  • Sheng Tao Yuan,
  • Li Sun

DOI
https://doi.org/10.3329/bjp.v12i4.32995
Journal volume & issue
Vol. 12, no. 4

Abstract

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The aim of this study was to investigate the hypoglycemic effect of Camellia chrysantha using type 2 diabetic mice model. The ethyl acetate/dichloromethane extract exhibited the most effective hypoglycemic effect. Compared to model group, all the three groups of C. chrysantha extracts significantly improved the mice’s behavioral performance, weight, reduced water and food intake. The ethyl acetate/dichloromethane extract of C. chrysantha significantly reduced the blood glucose level in the first week after administration and the crude extract also showed a significant effect after longer time administration. All the three extracts reduced the fasting blood glucose level to a certain extent and ethyl acetate/dichloromethane extract exhibited most significant effect among all the three extracts. Video Clip of Methodology: 1 min 31 sec Full Screen Alternate

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