Memorias do Instituto Oswaldo Cruz (Aug 2000)

Acidic ribosomal proteins and histone H3 from Leishmania present a high rate of divergence

  • Ysabel Montoya,
  • Carlos Padilla,
  • Maxy De Los Santos,
  • Teresa Barreto,
  • Douglas Barker,
  • Carlos Carrillo

DOI
https://doi.org/10.1590/S0074-02762000000400025
Journal volume & issue
Vol. 95, no. 4
pp. 591 – 594

Abstract

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Another additional peculiarity in Leishmania will be discussed about of the amino acid divergence rate of three structural proteins: acidic ribosomal P1 and P2b proteins, and histone H3 by using multiple sequence alignment and dendrograms. These structural proteins present a high rate of divergence regarding to their homologous protein in Trypanosoma cruzi. At this regard, L. (V.) peruviana P1 and T. cruzi P1 showed 57.4% of divergence rate. Likewise, L. (V.) braziliensis histone H3 and acidic ribosomal P2 protein exhibited 31.8% and 41.7% respectively of rate of divergence in comparison with their homologous in T. cruzi.

Keywords