Nature Communications (Apr 2019)
Cryo-EM structures of the pore-forming A subunit from the Yersinia entomophaga ABC toxin
- Sarah J Piper,
- Lou Brillault,
- Rosalba Rothnagel,
- Tristan I Croll,
- Joseph K Box,
- Irene Chassagnon,
- Sebastian Scherer,
- Kenneth N Goldie,
- Sandra A Jones,
- Femke Schepers,
- Lauren Hartley-Tassell,
- Thomas Ve,
- Jason N Busby,
- Julie E Dalziel,
- J Shaun Lott,
- Ben Hankamer,
- Henning Stahlberg,
- Mark R H Hurst,
- Michael J Landsberg
Affiliations
- Sarah J Piper
- School of Chemistry and Molecular Biosciences, The University of Queensland
- Lou Brillault
- School of Chemistry and Molecular Biosciences, The University of Queensland
- Rosalba Rothnagel
- Institute for Molecular Bioscience, The University of Queensland
- Tristan I Croll
- Cambridge Institute of Medical Research, University of Cambridge
- Joseph K Box
- School of Chemistry and Molecular Biosciences, The University of Queensland
- Irene Chassagnon
- School of Chemistry and Molecular Biosciences, The University of Queensland
- Sebastian Scherer
- Centre for Cellular Imaging and NanoAnalytics, Biozentrum, University of Basel
- Kenneth N Goldie
- Centre for Cellular Imaging and NanoAnalytics, Biozentrum, University of Basel
- Sandra A Jones
- Forage Science Group, AgResearch
- Femke Schepers
- Faculty of Science, Leiden University
- Lauren Hartley-Tassell
- Institute for Glycomics, Griffith University
- Thomas Ve
- Institute for Glycomics, Griffith University
- Jason N Busby
- School of Biological Sciences, University of Auckland
- Julie E Dalziel
- Food & Bio-based Products Group, AgResearch
- J Shaun Lott
- School of Biological Sciences, University of Auckland
- Ben Hankamer
- Institute for Molecular Bioscience, The University of Queensland
- Henning Stahlberg
- Centre for Cellular Imaging and NanoAnalytics, Biozentrum, University of Basel
- Mark R H Hurst
- Forage Science Group, AgResearch
- Michael J Landsberg
- School of Chemistry and Molecular Biosciences, The University of Queensland
- DOI
- https://doi.org/10.1038/s41467-019-09890-8
- Journal volume & issue
-
Vol. 10,
no. 1
pp. 1 – 12
Abstract
YenTcA is the pore-forming and membrane binding subunit of the ABC toxin YenTc, which is produced by the insect pathogen Yersinia entomophaga. Here authors present cryo-EM structures of YenTcA purified from the native source which implicate associated endochitinases in host cell recognition.
