Journal of Laboratory Physicians (Dec 2023)

Subphenotypes of SARS-CoV-2-Associated ARDS Overlap Each Other: A Retrospective Analysis

  • Parvathy R. Nair,
  • Kavitha Girish,
  • Gouri Mini,
  • Tazeen Khan,
  • Damarla Haritha,
  • Koninica Sanyal,
  • Sulagna Bhattacharjee,
  • Dalim K. Baidya,
  • Bikash R. Ray,
  • Rahul K. Anand,
  • Sudip K. Datta,
  • Manish Soneja,
  • Rajeshwari Subramaniam,
  • Souvik Maitra

DOI
https://doi.org/10.1055/s-0043-1768952
Journal volume & issue
Vol. 15, no. 04
pp. 558 – 561

Abstract

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Background Severe acute respiratory syndrome coronavirus 2 (SARS-CoV-2) virus-associated pneumonia and acute respiratory distress syndrome (ARDS) were often associated with hyperinflammation and elevation of several serum inflammatory markers but usually less than what is observed in non-coronavirus disease (COVID) ARDS. Elevated inflammatory markers such as C-reactive protein, interleukin (IL)-6, etc., are associated with severe infection. This study identified subphenotypes of COVID-19 ARDS patients by latent profile analysis in a cohort of Indian patients.

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