Range adaptation in schizophrenia: A one-year longitudinal study

Ling-ling Wang; Jing-bo Gong; Yi-hang Huang; Shu-hong Shi; Chao Yan; Hui-xin Hu; Yi Wang; Simon S.Y. Lui; Kang Ju; Raymond C.K. Chan

Schizophrenia Research: Cognition (Mar 2024)

Range adaptation in schizophrenia: A one-year longitudinal study

Ling-ling Wang,
Jing-bo Gong,
Yi-hang Huang,
Shu-hong Shi,
Chao Yan,
Hui-xin Hu,
Yi Wang,
Simon S.Y. Lui,
Kang Ju,
Raymond C.K. Chan

Affiliations

Ling-ling Wang: School of Psychology, Shanghai Normal University, Shanghai, China; Neuropsychology and Applied Cognitive Neuroscience Laboratory, CAS Key Laboratory of Mental Health, Institute of Psychology, Chinese Academy of Sciences, Beijing, China; Department of Psychology, University of Chinese Academy of Sciences, Beijing, China
Jing-bo Gong: Shanghai Changning Mental Health Center, Shanghai, China
Yi-hang Huang: Neuropsychology and Applied Cognitive Neuroscience Laboratory, CAS Key Laboratory of Mental Health, Institute of Psychology, Chinese Academy of Sciences, Beijing, China; Department of Psychology, University of Chinese Academy of Sciences, Beijing, China
Shu-hong Shi: Shanghai Changning Mental Health Center, Shanghai, China; Key Laboratory of Brain Functional Genomics (MOE&STCSM), Shanghai Changning-ECNU Mental Health Center, School of Psychology and Cognitive Science, East China Normal University, Shanghai, China
Chao Yan: Shanghai Changning Mental Health Center, Shanghai, China; Key Laboratory of Brain Functional Genomics (MOE&STCSM), Shanghai Changning-ECNU Mental Health Center, School of Psychology and Cognitive Science, East China Normal University, Shanghai, China
Hui-xin Hu: Neuropsychology and Applied Cognitive Neuroscience Laboratory, CAS Key Laboratory of Mental Health, Institute of Psychology, Chinese Academy of Sciences, Beijing, China; Department of Psychology, University of Chinese Academy of Sciences, Beijing, China; Department of Psychology, School of Humanities and Social Sciences, Beijing Forestry University, Beijing, China
Yi Wang: Neuropsychology and Applied Cognitive Neuroscience Laboratory, CAS Key Laboratory of Mental Health, Institute of Psychology, Chinese Academy of Sciences, Beijing, China; Department of Psychology, University of Chinese Academy of Sciences, Beijing, China
Simon S.Y. Lui: Department of Psychiatry, School of Clinical Medicine, The University of Hong Kong, Hong Kong
Kang Ju: Shanghai Changning Mental Health Center, Shanghai, China; Corresponding authors at: Institute of Psychology, Chinese Academy of Sciences, 16 Lincui Road, Beijing 100101, China; Shanghai Changning Mental Health Center, 299 Xiehe Road, Shanghai, 200335, China.
Raymond C.K. Chan: Neuropsychology and Applied Cognitive Neuroscience Laboratory, CAS Key Laboratory of Mental Health, Institute of Psychology, Chinese Academy of Sciences, Beijing, China; Department of Psychology, University of Chinese Academy of Sciences, Beijing, China; Corresponding authors at: Institute of Psychology, Chinese Academy of Sciences, 16 Lincui Road, Beijing 100101, China; Shanghai Changning Mental Health Center, 299 Xiehe Road, Shanghai, 200335, China.

Journal volume & issue: Vol. 35
p. 100297

Abstract

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Range adaptation refers to the representation of a stimulus value based on its relative position in the range of pre-experienced values. Altered range adaptation in value representation may be related to motivation and pleasure (MAP) deficit in schizophrenia (SCZ). This follow-up study examined the relationship between range adaptation performance and MAP symptoms in SCZ patients. We recruited 26 schizophrenia patients and followed them for 1 year. They completed an experimental task for estimating their range adaptation to outcome value (OV) and expected value (EV) at baseline and after 1 year. At baseline, we found a marginally significant and negative correlation between OV adaptation and avolition symptoms in SCZ patients. Moreover, the 1-year change of EV adaptation was significantly and negatively correlated with the change of self-report pleasure experience. Our results suggest that range adaptation may track the variations of MAP symptoms in SCZ.

Published in Schizophrenia Research: Cognition

ISSN: 2215-0013 (Online)
Publisher: Elsevier
Country of publisher: United States
LCC subjects: Medicine: Internal medicine: Neurosciences. Biological psychiatry. Neuropsychiatry: Neurology. Diseases of the nervous system
Website: http://www.journals.elsevier.com/schizophrenia-research-cognition/

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