Nature Communications (May 2019)

Bridging the gap between transition metal- and bio-catalysis via aqueous micellar catalysis

  • Margery Cortes-Clerget,
  • Nnamdi Akporji,
  • Jianguang Zhou,
  • Feng Gao,
  • Pengfei Guo,
  • Michael Parmentier,
  • Fabrice Gallou,
  • Jean-Yves Berthon,
  • Bruce H. Lipshutz

DOI
https://doi.org/10.1038/s41467-019-09751-4
Journal volume & issue
Vol. 10, no. 1
pp. 1 – 10

Abstract

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Chemo-enzymatic tandem processes allow access to more complex non-racemic products. Here, the authors show that non-ionic surfactants, especially the tailor-made surfactant TPGS-750-M, enhance the activity of alcohol dehydrogenase to afford stereopure products in a 1-pot reaction.