Nature Communications (Dec 2018)

The gut microbiome is required for full protection against acute arsenic toxicity in mouse models

  • Michael Coryell,
  • Mark McAlpine,
  • Nicholas V. Pinkham,
  • Timothy R. McDermott,
  • Seth T. Walk

DOI
https://doi.org/10.1038/s41467-018-07803-9
Journal volume & issue
Vol. 9, no. 1
pp. 1 – 9

Abstract

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It is unclear whether the gut microbiome can mitigate or exacerbate arsenic toxicity. Here, Coryell et al. show that the human gut microbiome protects mice from arsenic-induced mortality, with protection levels correlating with the relative abundance of the human commensal Faecalibacterium.