Journal of Integrative Bioinformatics (Jun 2020)

Synthetic biology open language visual (SBOL visual) version 2.2

  • Baig Hasan,
  • Fontanarrosa Pedro,
  • Kulkarni Vishwesh,
  • McLaughlin James,
  • Vaidyanathan Prashant,
  • Bartley Bryan,
  • Bhatia Swapnil,
  • Bhakta Shyam,
  • Bissell Michael,
  • Clancy Kevin,
  • Cox Robert Sidney,
  • Moreno Angel Goñi,
  • Gorochowski Thomas,
  • Grunberg Raik,
  • Luna Augustin,
  • Madsen Curtis,
  • Misirli Goksel,
  • Nguyen Tramy,
  • Le Novere Nicolas,
  • Palchick Zachary,
  • Pocock Matthew,
  • Roehner Nicholas,
  • Sauro Herbert,
  • Scott-Brown James,
  • Sexton John T.,
  • Stan Guy-Bart,
  • Tabor Jeffrey J.,
  • Vilar Marta Vazquez,
  • Voigt Christopher A.,
  • Wipat Anil,
  • Zong David,
  • Zundel Zach,
  • Beal Jacob,
  • Myers Chris

DOI
https://doi.org/10.1515/jib-2020-0014
Journal volume & issue
Vol. 17, no. 2-3

Abstract

Read online

People who are engineering biological organisms often find it useful to communicate in diagrams, both about the structure of the nucleic acid sequences that they are engineering and about the functional relationships between sequence features and other molecular species. Some typical practices and conventions have begun to emerge for such diagrams. The Synthetic Biology Open Language Visual (SBOL Visual) has been developed as a standard for organizing and systematizing such conventions in order to produce a coherent language for expressing the structure and function of genetic designs. This document details version 2.2 of SBOL Visual, which builds on the prior SBOL Visual 2.1 in several ways. First, the grounding of molecular species glyphs is changed from BioPAX to SBO, aligning with the use of SBO terms for interaction glyphs. Second, new glyphs are added for proteins, introns, and polypeptide regions (e. g., protein domains), the prior recommended macromolecule glyph is deprecated in favor of its alternative, and small polygons are introduced as alternative glyphs for simple chemicals.

Keywords