Diagnostics (Jun 2020)

“Noninfective Endocarditis”: A Case Report of Hereditary Coagulation Disorders in a 28-Year-Old Male

  • Gregory Reid,
  • Luca Koechlin,
  • Oliver Reuthebuch,
  • Florian Rüter,
  • Helmut Hopfer,
  • Friedrich Eckstein,
  • David Santer

DOI
https://doi.org/10.3390/diagnostics10060384
Journal volume & issue
Vol. 10, no. 6
p. 384

Abstract

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We report a case of a young male who presented with acute limb ischemia after sport. With no prior history of disease, a non-infective endocarditis of the native aortic valve was diagnosed. After surgical valve replacement, the patient suffered from acute myocardial ischemia under phenprocoumon therapy. Anti-coagulant monitoring was subsequently changed to Factor II analysis after a rare Factor VII deficiency and prothrombin mutation (G20210A) was diagnosed.

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