Nature Communications (Oct 2019)

Colonizing multidrug-resistant bacteria and the longitudinal evolution of the intestinal microbiome after liver transplantation

  • Medini K. Annavajhala,
  • Angela Gomez-Simmonds,
  • Nenad Macesic,
  • Sean B. Sullivan,
  • Anna Kress,
  • Sabrina D. Khan,
  • Marla J. Giddins,
  • Stephania Stump,
  • Grace I. Kim,
  • Ryan Narain,
  • Elizabeth C. Verna,
  • Anne-Catrin Uhlemann

DOI
https://doi.org/10.1038/s41467-019-12633-4
Journal volume & issue
Vol. 10, no. 1
pp. 1 – 12

Abstract

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In a large prospective cohort of liver transplantation (LT) recipients, the authors identify associations between colonization by multidrug-resistant bacteria (MDRB) and microbiome dysbiosis pre- and post-LT, suggesting colonizing MDRB as an important target for microbiome-informed therapeutic approaches post-LT.