Comparative evaluation of dithranol-loaded nanosponges fabricated by solvent evaporation technique and melt method

Abstract

Highlights Comparative evaluation of melt and solvent evaporation techniques for synthesis of dithranol nanosponges. The particle characteristics were investigated using FTIR, DSC, PXRD and surface morphology. Tuning of size and crystallinity of nanosponges were achieved by tuning synthetic techniques. Antioxidant and photostability properties of the dithranol nanosponges were efficiently correlated.

Keywords

• β-Cyclodextrin
• Diphenylcarbonate
• Solubility
• DPPH assay
• Photostability
• Atomic force microscopy