Nature Communications (Jan 2023)

Uncovering a miltiradiene biosynthetic gene cluster in the Lamiaceae reveals a dynamic evolutionary trajectory

  • Abigail E. Bryson,
  • Emily R. Lanier,
  • Kin H. Lau,
  • John P. Hamilton,
  • Brieanne Vaillancourt,
  • Davis Mathieu,
  • Alan E. Yocca,
  • Garret P. Miller,
  • Patrick P. Edger,
  • C. Robin Buell,
  • Björn Hamberger

DOI
https://doi.org/10.1038/s41467-023-35845-1
Journal volume & issue
Vol. 14, no. 1
pp. 1 – 14

Abstract

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A diterpenoid biosynthetic gene cluster (BGC) has been identified in a few species in the Lamiaceae (mint) family, but its origin and evolution remain unclear. Here, the authors report assembly of genomes of three species within the family and reveal the dynamic evolutionary trajectory of the BGC.