A1298C Polymorphism of Fetal Methylenetetrahydrofolate Reductase (MTHFR) Gene as a Risk Factor for Spontaneous Abortion

Isah Sulfiana; St Maisuri T Chalid; Retno B Farid; Syahrul Rauf; Eddy Hartono

doi:10.32771/inajog.v4i2.77

Indonesian Journal of Obstetrics and Gynecology (Apr 2016)

A1298C Polymorphism of Fetal Methylenetetrahydrofolate Reductase (MTHFR) Gene as a Risk Factor for Spontaneous Abortion

Isah Sulfiana,
St Maisuri T Chalid,
Retno B Farid,
Syahrul Rauf,
Eddy Hartono

Affiliations

Isah Sulfiana: Faculty of Medicine University of Hasanudin/ Dr. Wahidin Sudirohusodo Hospital Makassar
St Maisuri T Chalid: Faculty of Medicine University of Hasanudin/ Dr. Wahidin Sudirohusodo Hospital Makassar
Retno B Farid: Faculty of Medicine University of Hasanudin/ Dr. Wahidin Sudirohusodo Hospital Makassar
Syahrul Rauf: Faculty of Medicine University of Hasanudin/ Dr. Wahidin Sudirohusodo Hospital Makassar
Eddy Hartono: Faculty of Medicine University of Hasanudin/ Dr. Wahidin Sudirohusodo Hospital Makassar

DOI: https://doi.org/10.32771/inajog.v4i2.77

Abstract

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Objective: To investigate the role of A1298C polymorphism of fetal methylenetetrahydrofolate reductase (MTHFR) gene in spontaneous abortion. Method: The case control study design recruited 96 subjects in Siti Fatimah and Pertiwi mother and child hospital, Dr. Wahidin Sudirohusodo, Pelamonia, Bhayangkara, Syekh Yusuf, Haji and Labuang Baji hospital from March to September 2014. All subjects fulfilling the inclusion criteria were taken tissue samples from mothers experiencing spontaneous abortion and blood samples from normally born baby. The data were analyzed using Pearson chi-square with significant rate of 5% (p

Published in Indonesian Journal of Obstetrics and Gynecology

ISSN: 2338-6401 (Print); 2338-7335 (Online)
Publisher: Indonesian Society of Obstetrics and Gynecology
Country of publisher: Indonesia
LCC subjects: Medicine: Gynecology and obstetrics
Website: http://inajog.com/index.php/journal

About the journal