Frontiers in Pediatrics (May 2021)

Prophylactic Erythropoietin for Neuroprotection in Very Preterm Infants: A Meta-Analysis Update

  • Hendrik S. Fischer,
  • Nora J. Reibel,
  • Christoph Bührer,
  • Christof Dame

DOI
https://doi.org/10.3389/fped.2021.657228
Journal volume & issue
Vol. 9

Abstract

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A meta-analysis update of randomized controlled trials investigating recombinant human erythropoietin suggests improved neurodevelopmental outcome in preterm infants. There was substantial heterogeneity, which could be ascribed to a single trial. Exclusion of this trial featuring a high risk of bias abolished heterogeneity and any effects of recombinant human erythropoietin treatment.

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