Direct experimental observation of blue-light-induced conformational change and intermolecular interactions of cryptochrome

Pei Li; Huaqiang Cheng; Vikash Kumar; Cecylia Severin Lupala; Xuanxuan Li; Yingchen Shi; Chongjun Ma; Keehyoung Joo; Jooyoung Lee; Haiguang Liu; Yan-Wen Tan

doi:10.1038/s42003-022-04054-9

Communications Biology (Oct 2022)

Direct experimental observation of blue-light-induced conformational change and intermolecular interactions of cryptochrome

Pei Li,
Huaqiang Cheng,
Vikash Kumar,
Cecylia Severin Lupala,
Xuanxuan Li,
Yingchen Shi,
Chongjun Ma,
Keehyoung Joo,
Jooyoung Lee,
Haiguang Liu,
Yan-Wen Tan

Affiliations

Pei Li: State Key Laboratory of Surface Physics, Department of Physics, Fudan University
Huaqiang Cheng: State Key Laboratory of Surface Physics, Department of Physics, Fudan University
Vikash Kumar: Beijing Computational Science Research Center
Cecylia Severin Lupala: Beijing Computational Science Research Center
Xuanxuan Li: Beijing Computational Science Research Center
Yingchen Shi: Beijing Computational Science Research Center
Chongjun Ma: State Key Laboratory of Surface Physics, Department of Physics, Fudan University
Keehyoung Joo: Center for Advanced Computation, Korea Institute for Advanced Study
Jooyoung Lee: School of Computational Sciences, Korea Institute for Advanced Study
Haiguang Liu: Beijing Computational Science Research Center
Yan-Wen Tan: State Key Laboratory of Surface Physics, Department of Physics, Fudan University

DOI: https://doi.org/10.1038/s42003-022-04054-9
Journal volume & issue: Vol. 5, no. 1
pp. 1 – 13

Abstract

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Refined structures, protein-docking analysis and single molecule assays provides insights into light-induced conformational changes in the cryptochrome CraCRY.

Published in Communications Biology

ISSN: 2399-3642 (Online)
Publisher: Nature Portfolio
Country of publisher: United Kingdom
LCC subjects: Science: Biology (General)
Website: https://www.nature.com/commsbio/

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