Остеопороз и остеопатии (Aug 2008)

GIPERPARATIREOZ POSLEALLOTRANSPLANTATsII TRUPNOY POChKII ORTOTOPIChESKOY TRANSPLANTATsII SERDTsA

  • I. A. PRONChENKO,
  • I. P. ERMAKOVA,
  • N. A. TOMILINA,
  • R. N. VEDERNIKOVA,
  • T. K. KOLIAShVILI,
  • V. P. BUZULINA,
  • E. N. KAZAKOV,
  • A. Ya. KORMER,
  • V. I. ShUMAKOV

DOI
https://doi.org/10.14341/osteo2008216-21
Journal volume & issue
Vol. 11, no. 2
pp. 16 – 21

Abstract

Read online

Analyses of frequency, rate, main rise mechanisms of hyperparatyroidism and its role in bone losses were estimated in crossmatch research of 158 kidney and 25 heart recipients. Hyperparathyroidism frequency was more following kidney then heart transplantation (74% vs 36%, p=0,000), PTH level being higher in kidney recipients and in women higher then in men with kidney transplant. Hyperparathyroidism in women was associated with hemodialysis duration before operation and the estrogen level which was more in pre- then in postmenopause while PTH level was lesser in pre- then postmenopause. In men PTH level as in heart as in kidney groups was associated with renal function and cumulative prednisolone doses. Hyperparathyroidism in men and women after kidney transplantation followed aхial BMD losses so as in men after kidney and heart transplantation -periferal skeleton (femoral neck) BMD losses.