Improved Method for Preparation of 3-(1H-Indol-3-yl)benzofuran-2(3H)-ones

Igor Yu. Grishin; Nikolai A. Arutiunov; Dmitrii A. Aksenov; Nicolai A. Aksenov; Alexander V. Aksenov; Amina Z. Gasanova; Elena A. Sorokina; Carolyn Lower; Michael Rubin

doi:10.3390/molecules27061902

Molecules (Mar 2022)

Improved Method for Preparation of 3-(1H-Indol-3-yl)benzofuran-2(3H)-ones

Igor Yu. Grishin,
Nikolai A. Arutiunov,
Dmitrii A. Aksenov,
Nicolai A. Aksenov,
Alexander V. Aksenov,
Amina Z. Gasanova,
Elena A. Sorokina,
Carolyn Lower,
Michael Rubin

Affiliations

Igor Yu. Grishin: Department of Chemistry and Pharmacy, North Caucasus Federal University, 1a Pushkin St., 355017 Stavropol, Russia
Nikolai A. Arutiunov: Department of Chemistry and Pharmacy, North Caucasus Federal University, 1a Pushkin St., 355017 Stavropol, Russia
Dmitrii A. Aksenov: Department of Chemistry and Pharmacy, North Caucasus Federal University, 1a Pushkin St., 355017 Stavropol, Russia
Nicolai A. Aksenov: Department of Chemistry and Pharmacy, North Caucasus Federal University, 1a Pushkin St., 355017 Stavropol, Russia
Alexander V. Aksenov: Department of Chemistry and Pharmacy, North Caucasus Federal University, 1a Pushkin St., 355017 Stavropol, Russia
Amina Z. Gasanova: Department of Chemistry and Pharmacy, North Caucasus Federal University, 1a Pushkin St., 355017 Stavropol, Russia
Elena A. Sorokina: Organic Chemistry Department, Peoples’ Friendship University of Russia (RUDN University), 6 Miklukho-Maklaya St., 117198 Moscow, Russia
Carolyn Lower: Department of Chemistry, University of Kansas, 1567 Irving Hill Road, Lawrence, KS 66045, USA
Michael Rubin: Department of Chemistry and Pharmacy, North Caucasus Federal University, 1a Pushkin St., 355017 Stavropol, Russia

DOI: https://doi.org/10.3390/molecules27061902
Journal volume & issue: Vol. 27, no. 6
p. 1902

Abstract

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3-(1H-Indol-3-yl)benzofuran-2(3H)-ones were efficiently accessed via polyphosphoric acid-mediated condensation of 3-(2-nitrovinyl)-1H-indoles with phenols.

Published in Molecules

ISSN: 1420-3049 (Online)
Publisher: MDPI AG
Country of publisher: Switzerland
LCC subjects: Science: Chemistry: Organic chemistry
Website: http://www.mdpi.com/journal/molecules

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