Ameliorative Role of Diet in some Immunological and Metabolic Indicators

Abstract

The study aimed to show the effect of diet in observing some immunological and physiological aspects of the human body. The study is divided into two parts; the first part includes the immunological markers that involve interleukins (IL1α, IL 17,) and high-sensitivity C-reactive protein (hs-CRP). The second part includes biochemical markers; Vitamin D, Total cholesterol, Triglyceride, HDL, LDL, and Calcium. These parameters were measured in blood from 120 volunteers and their age (34.5 ± 9. 13) for men, and (27.4 ± 7.74) for women. However, the current study included two groups: Group - A (Include men blood pre and post-diet), and Group- B (Include blood sample of women pre and post-diet). IL1α, IL 17, hs-CRP, and Vitamin D were measured by using Sandwich Enzyme-Linked Immune-Sorbent assay technique (ELISA) while Total cholesterol, Triglyceride, HDL, LDL, and calcium were estimated by using the enzymatic colorimetric method. The average weight for men were (pre-diet = 94.1 ± 7.74; post-diet = 79.1 ± 12.8) while for women were (pre-diet = 78.3 ± 13.7; post-diet = 66.1 ± 10.3). The study noted that there is a statistically significant difference between groups (p<0.05) for the following indicators: Vitamin D, Total cholesterol, and group B for calcium assay. The study revealed that the results were non-significant between groups for parameters: IL1α, IL17, hs-CRP, Tg, HDL, and group A for calcium assay.

Keywords

• interleukin-17
• il1α
• hs-crp
• weight
• obesity
• lipid profile
• calcium