Changes in adipokine indicators depending on A1166C polymorphism of the angiotensin II type 1 receptor gene as a predictor of the arterial hypertension

Pidruchna Svitlana; Shmanko Volodymyr; Zakharchuk Uliana; Tokarskyy Oleksandr; Hnizdyukh Roman; Lynkhatskyi Petro; Kuzmak Iryna; Yaroshenko Tetyana; Bandas Iryna; Vasylyshyn Nadija; Ostrivka Oksana; Mudra Alla; Palytsya Liliya; Letniak Nataliya; Pohorielova Oksana

doi:10.2478/enr-2024-0017

Endocrine Regulations (Jan 2024)

Changes in adipokine indicators depending on A1166C polymorphism of the angiotensin II type 1 receptor gene as a predictor of the arterial hypertension

Pidruchna Svitlana,
Shmanko Volodymyr,
Zakharchuk Uliana,
Tokarskyy Oleksandr,
Hnizdyukh Roman,
Lynkhatskyi Petro,
Kuzmak Iryna,
Yaroshenko Tetyana,
Bandas Iryna,
Vasylyshyn Nadija,
Ostrivka Oksana,
Mudra Alla,
Palytsya Liliya,
Letniak Nataliya,
Pohorielova Oksana

Affiliations

Pidruchna Svitlana: Department of Medical Biochemistry, I. Horbachevsky Ternopil National Medical University of the Ministry of Health of Ukraine
Shmanko Volodymyr: Department of Farmacology and Clinical Farmacology, I. Horbachevsky Ternopil National Medical University Ternopil, Ukraine
Zakharchuk Uliana: MSD BIOTECH, Swords, Ireland
Tokarskyy Oleksandr: Department of Medical Biochemistry, I. Horbachevsky Ternopil National Medical University of the Ministry of Health of Ukraine
Hnizdyukh Roman: Department of Farmacology and Clinical Farmacology, I. Horbachevsky Ternopil National Medical University Ternopil, Ukraine
Lynkhatskyi Petro: Department of Medical Biochemistry, I. Horbachevsky Ternopil National Medical University of the Ministry of Health of Ukraine
Kuzmak Iryna: Department of Medical Biochemistry, I. Horbachevsky Ternopil National Medical University of the Ministry of Health of Ukraine
Yaroshenko Tetyana: Department of Medical Biochemistry, I. Horbachevsky Ternopil National Medical University of the Ministry of Health of Ukraine
Bandas Iryna: Department of Medical Biochemistry, I. Horbachevsky Ternopil National Medical University of the Ministry of Health of Ukraine
Vasylyshyn Nadija: Department of Medical Biochemistry, I. Horbachevsky Ternopil National Medical University of the Ministry of Health of Ukraine
Ostrivka Oksana: Department of Medical Biochemistry, I. Horbachevsky Ternopil National Medical University of the Ministry of Health of Ukraine
Mudra Alla: Department of Medical Biochemistry, I. Horbachevsky Ternopil National Medical University of the Ministry of Health of Ukraine
Palytsya Liliya: Department of Medical Biochemistry, I. Horbachevsky Ternopil National Medical University of the Ministry of Health of Ukraine
Letniak Nataliya: Department of Medical Biochemistry, I. Horbachevsky Ternopil National Medical University of the Ministry of Health of Ukraine
Pohorielova Oksana: Department of Ecology and Healthcare West Ukrainian National University Ternopil, Ukraine

DOI: https://doi.org/10.2478/enr-2024-0017
Journal volume & issue: Vol. 58, no. 1
pp. 153 – 157

Abstract

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Objective. Genetic factors substantially contribute to the development and duration of arterial hypertension. The study of the A1166C polymorphism of the angiotensin II type 1 receptor gene (AGTR1) in arterial hypertension is an auspicious area for assessing the relationship between heredity, hypertension development, and adipokines, but it still remains debatable. The purpose of the current study was to investigate serum adipokines levels depending on the AGTR1 A1166C polymorphism.

Published in Endocrine Regulations

ISSN: 1336-0329 (Online)
Publisher: Sciendo
Country of publisher: Poland
LCC subjects: Medicine: Internal medicine: Specialties of internal medicine: Diseases of the endocrine glands. Clinical endocrinology
Website: https://sciendo.com/journal/ENR

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