Plastic and Reconstructive Surgery, Global Open (May 2023)

The Peripheral Nerve Surgeon’s Role in the Management of Neuropathic Pain

  • Seamus P. Caragher, BS, MPhil,
  • Kimberly S. Khouri, MD,
  • Floris V. Raasveld, MD,
  • Jonathan M. Winograd, MD,
  • Ian L. Valerio, MD, MS, MBA,
  • Lisa Gfrerer, MD, PhD,
  • Kyle R. Eberlin, MD

DOI
https://doi.org/10.1097/GOX.0000000000005005
Journal volume & issue
Vol. 11, no. 5
p. e5005

Abstract

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Summary:. Neuropathic pain (NP) underlies significant morbidity and disability worldwide. Although pharmacologic and functional therapies attempt to address this issue, they remain incompletely effective for many patients. Peripheral nerve surgeons have a range of techniques for intervening on NP. The aim of this review is to enable practitioners to identify patients with NP who might benefit from surgical intervention. The workup for NP includes patient history and specific physical examination maneuvers, as well as imaging and diagnostic nerve blocks. Once diagnosed, there is a range of options surgeons can utilize based on specific causes of NP. These techniques include nerve decompression, nerve reconstruction, nerve ablative techniques, and implantable nerve-modulating devices. In addition, there is an emerging role for preoperative involvement of peripheral nerve surgeons for cases known to carry a high risk of inducing postoperative NP. Lastly, we describe the ongoing work that will enable surgeons to expand their armamentarium to better serve patients with NP.