Genel Tıp Dergisi (Dec 2023)

Hpv-Specific Risk Management in Cervical Pathology Screening and Comparison of Pathological Results

  • Ali Acar,
  • Tuğçehan Şimşekler,
  • Emine Türen Demir,
  • Fatih Akkuş,
  • Şeyma Çiçek,
  • Sıtkı Özbilgeç

DOI
https://doi.org/10.54005/geneltip.1340317
Journal volume & issue
Vol. 33, no. 6
pp. 775 – 778

Abstract

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Background: In the process of detecting cervical cancer, cytology and HPV genotype screening both play a significant part. More researches are required to determine whether or not multiple HPV genotyping can accurately predict cytological abnormalities. Methods: A total of 696 female individuals were subjected to analysis for cytology and HPV genotype testing. HPV-DNA, smear and final pathology results of these patients and the relationship between them were investigated using statistical methods. Results: Cytological data indicating abnormalities were seen in a total of 110 subjects. HPV-16 was determined to be the most prevalent variety among the patients, and HPV-16-positive females were found to have an elevated risk of cervical lesions. HPV 16 infection rates were substantially increased in patients with HSIL and higher lesions. Conclusion: An infection caused by HPV-16 is a major risk factor for cervical lesions. A test that examines many HPV genotypes may be able to predict cytological problems.

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