Exploring the Efficacy of Using Geotrichum fermentans, Rhodotorula rubra, Kluyveromyce marxiamus, Clay Minerals, and Walnut Nutshells for Mycotoxin Remediation

Gintarė Vaičiulienė; Jurgita Jovaišienė; Rimvydas Falkauskas; Algimantas Paškevičius; Neringa Sutkevičienė; Audronė Rekešiūtė; Šarūnė Sorkytė; Violeta Baliukonienė

doi:10.3390/toxins16060281

Toxins (Jun 2024)

Exploring the Efficacy of Using Geotrichum fermentans, Rhodotorula rubra, Kluyveromyce marxiamus, Clay Minerals, and Walnut Nutshells for Mycotoxin Remediation

Gintarė Vaičiulienė,
Jurgita Jovaišienė,
Rimvydas Falkauskas,
Algimantas Paškevičius,
Neringa Sutkevičienė,
Audronė Rekešiūtė,
Šarūnė Sorkytė,
Violeta Baliukonienė

Affiliations

Gintarė Vaičiulienė: Animal Reproduction Laboratory, Large Animal Clinic, Veterinary Academy, Lithuanian University of Health Sciences, Tilzes Str. 18, LT-47181 Kaunas, Lithuania
Jurgita Jovaišienė: Department of Food Safety and Quality, Veterinary Academy, Lithuanian University of Health Sciences, Tilzes Str. 18, LT-47181 Kaunas, Lithuania
Rimvydas Falkauskas: National Food and Veterinary Risk Assessment Institute, J. Kairiukscio Str. 10, LT-08411 Vilnius, Lithuania
Algimantas Paškevičius: Laboratory of Biodeterioration Research, Institute of Botany, Nature Research Centre, Akademijos Str. 2, LT-08412 Vilnius, Lithuania
Neringa Sutkevičienė: Animal Reproduction Laboratory, Large Animal Clinic, Veterinary Academy, Lithuanian University of Health Sciences, Tilzes Str. 18, LT-47181 Kaunas, Lithuania
Audronė Rekešiūtė: Animal Reproduction Laboratory, Large Animal Clinic, Veterinary Academy, Lithuanian University of Health Sciences, Tilzes Str. 18, LT-47181 Kaunas, Lithuania
Šarūnė Sorkytė: Animal Reproduction Laboratory, Large Animal Clinic, Veterinary Academy, Lithuanian University of Health Sciences, Tilzes Str. 18, LT-47181 Kaunas, Lithuania
Violeta Baliukonienė: Department of Food Safety and Quality, Veterinary Academy, Lithuanian University of Health Sciences, Tilzes Str. 18, LT-47181 Kaunas, Lithuania

DOI: https://doi.org/10.3390/toxins16060281
Journal volume & issue: Vol. 16, no. 6
p. 281

Abstract

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The aim of this study was to evaluate the effectiveness of nine different biological compounds to reduce mycotoxins concentrations. The hypothesis of this study was that a static in vitro gastrointestinal tract model, as an initial screening tool, can be used to simulate the efficacy of Geotrichum fermentans, Rhodotorula rubra, Kluyveromyce marxiamus yeast cell walls and their polysaccharides, red and white clay minerals, and walnuts nutshells claiming to detoxify AFB1, ZEA, DON, and T-2 toxin mycotoxins. Mycotoxin concentrations were analyzed using high-performance liquid chromatography (HPLC) with fluorescent (FLD) and ultraviolet detectors (UV). The greatest effects on reducing mycotoxin concentrations were determined as follows: for AFB1, inserted G. fermentans cell wall polysaccharides and walnut nutshells; for ZEA, inserted R. rubra and G. fermentans cell walls and red clay minerals; for DON, R. rubra cell wall polysaccharides and red clay minerals; and for T-2 toxin, R. rubra cell walls, K. marxianus, and G. fermentans cell wall polysaccharides and walnut nutshells. The present study indicated that selected mycotoxin-detoxifying biological compounds can be used to decrease mycotoxin concentrations.

Published in Toxins

ISSN: 2072-6651 (Online)
Publisher: MDPI AG
Country of publisher: Switzerland
LCC subjects: Medicine
Website: http://www.mdpi.com/journal/toxins/

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