Clinical Manifestations and Outcome of I Inspitalised Babies with Birth Asphyxia in Sagamu

Abstract

Background: Birth asphyxia a leading cause of neonatal morbidityand mortality in developing routitries of the world but there is inadequate local data. Objectives. To study ex clinical course of neonates hospitalise with birth asphysi, document the pattern of morbidity, and determine risk factors for curtality among them. Methods: Casesot hirthaspleyxia admitted to the socalal unit of Ohhisi Owoharjo University Teaching Hospital (QOUTH), Saganul a tetuary lealth institution locate in south-western Nigeria were prospectively stuched relevant prestata perinatal hispory presenting features, dirical course. labor spory findings and outcome of treatment were reorded for analysis. Possible risk factors for mortality were explored using aniciple regression atladys. Results: There were 459 neonatal admissions over the 18 month period of study. One hundred and fourteen (24.8 percent of these were cases of birth asphyxia Tlie male to female ratio was 1.9:1 and mean (SD) body weight, 2.8 (0.8) kg. Thirty seven percent of the 81 habies for won gestational age was recorders were preterin Maternal hypertension, toxaetin ol pregnancy un prolonged labour were the cajur prenatal factors associated with birth asphyxia. Comore complications observed among the patients included wypoxic-ischemic cncephalopachy aletabolic acidosis, hypoglycaemia, transient rental insufficiency and hypocalcaemia. Seventy coveu (67.5 percent) hahies were discharged in satisfactory wxlition while the case fatalicy rate wils 29.8 percent with prentunity, Jeep coma at presentation and Doncurrent anacmia emerging & significant predictors of mortality Conclusion: Mormality was high among intacs hospitalised for birth asplıyxia itt hus study The reajur risk facons identified included prematurity, severe encephalopathy and atema