Factors related to survival outcomes following orbital exenteration: a retrospective, comparative, case series

Abstract

Abstract Background Orbital exenteration is a disfiguring procedure that aims to achieve local control. It is commonly a part of the management of malignant orbital tumor which is a life-threatening condition. It is necessary to determine predictive factors associated with overall survival (OS) following orbital exenteration. Methods This was a retrospective, comparative, case series of 39 patients with malignant tumors who underwent orbital exenteration. Patient records were reviewed for age, clinical presentation, preoperative visual acuity (VA), tumor size, surgical margin, tumor invasiveness, recurrent disease, and status of distant metastasis. Kaplan-Meier curves were used to assess OS and event-free survival (EFS). The predictive factors related to OS were identified using multivariate analysis. Results The mean age was 62.9 years (range, 5.5 to 89.7 years), 68.4% presented with VA 20 mm, and distant metastasis at diagnosis mostly due to patient negligence.

Keywords

• Orbital exenteration
• Predictive factor
• Metastasis
• Overall survival