Journal of Clinical Medicine (Aug 2023)

The ABC of Heart Transplantation—Part 1: Indication, Eligibility, Donor Selection, and Surgical Technique

  • Daniele Masarone,
  • Michelle M. Kittleson,
  • Luigi Falco,
  • Maria L. Martucci,
  • Dario Catapano,
  • Benedetta Brescia,
  • Andrea Petraio,
  • Marisa De Feo,
  • Giuseppe Pacileo

DOI
https://doi.org/10.3390/jcm12165217
Journal volume & issue
Vol. 12, no. 16
p. 5217

Abstract

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Cardiac transplantation represents the gold standard of treatment for selected patients with advanced heart failure who have poor functional capacity and prognosis despite guideline-directed medical therapy and device-based therapy. Proper patient selection and appropriate referral of patients to centers for the treatment of advanced heart failure are the first but decisive steps for screening patients eligible for cardiac transplantation. The eligibility and the decision to list for cardiac transplantation, even for patients with relative contraindications, are based on a multidisciplinary evaluation of a transplant team. This review will discuss the practical indications, the process of patient eligibility for cardiac transplantation, the principle of donor selection, as well as the surgical technique.

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