Assessment of Antibiotic Resistance Pattern and Frequency of Gram-positive Bacteria Isolated from Urine Samples in Bandar Torkman

Abstract

Introductions: As antibiotic resistance in uropathogens is increasing, information on the most common etiologic agents and their antibiotic susceptibility are highly important. The aim of this study was to determine antibiotic resistance pattern of Gram-positive uropathogens isolated from urine specimens referred to clinical laboratories in Bandar Turkmen. Materials and Methods: Urine samples of patients suspected of urinary tract infection were collected from April through May 2016. From 367 positive urine samples, 89 samples were positive for Gram-positive Europathogens, using standard microbiological and biochemical tests. Then, antibiotic resistance patterns were determined by disk diffusion method. Results: The most isolated were Staphylococcus epidermidis (30), Streptococcus group B (28), Non-heamolytic streptococci (10) and Enterococci (7), Staphylococcus saprophyticus (6), Alpha-heamolytic Streptococci (5) and Micrococci (3) and the highest resistance was observed to ampicillin and cotrimoxazole. Moreover, all the isolates were sensitive to vancomycin. Conclusion: It is found that the most common causes of UTI were Staphylococcus epidermidis and Streptococcus group B, whichhad the highest antibiotic resistance to cotrimoxazole and ampicillin. They were also most susceptible to vancomycin, amikacin and ceftizoxime. Therefore, these antibiotics can be used in the empiric therapy of UTIs. .

Keywords

• antibiotic resistance
• gram-positive bacteria
• urinary tract infections