A Comparative Study of Serum Lipid Profile and Common Bile Duct Dimensions in Pre and Post Cholecystectomy Patients

Abstract

Introduction: Post cholecystectomy the common bile duct dilates in an effort to restore the storage function of gall bladder and helps in metabolism of lipids. There are many studies determining the association of abnormal lipid parameters with gall stones but there are not many studies comparing the diameter of CBD pre and post cholecystectomy and its clinical implication. Hence, under the light of above-mentioned data, we planned the present study to assess the effect of cholecystectomy on common bile duct diameter and lipid profile. Methodology: Patients with gall bladder stone eligible for cholecystectomy were included in the study. In this study pre and post operative cholecystectomy values of lipid profile and CBD diameter were compared. Patients were followed up till one year post operative to assess changes. Results: Out of total 55 cases included in the study 38.2% were male and 78.2% has mixed type of stone. Post operatively Serum cholesterol, triglyceride, HDL and LDL value improved significantly at the end of one year follow up (p<0.01). Pre operative mean CBD diameter was 4.38 mm which was increased to 5.6 mm at the end of one year post operatively (p<0.01) Conclusion: Cholecystectomy leads to significant impact on in lipid profile. Significant compensatory dilatation of common bile duct diameter occurs post cholecystectomy. This indicates a very positive impact of cholecystectomy on lipid profile.

Keywords

• Cholecystectomy
• Common Bile Duct
• Cholesterol
• Lipid Profile
• CBD diameter