MicroRNAs in Sepsis-Induced Acute Lung Injury: New Advances in Diagnostics and Therapeutic

Abstract

Abstract In this commentary, we explored the advances made in miRNA and sepsis-induced acute lung injury (ALI) from the perspective of diagnosis and treatment. miRNAs play an important role in sepsis-induced ALI, including the regulation of inflammation, apoptosis, and oxidative stress, thereby participating in the progression of sepsis-induced ALI. miRNAs can act as therapeutic or diagnostic targets of sepsis-induced ALI. Also, the development of alternative or inhibitory drugs targeting specific miRNAs may be of great significance in treating sepsis-induced ALI and improving the prognosis of sepsis patients.

Keywords

• miRNAs
• Sepsis
• Acute lung injury
• Diagnostics
• Therapeutic