CORRELATIONS BETWEEN VITAMIN D LEVEL AND THE PRESENCE OF LARGE CHRONIC PERIAPICAL LESIONS IN PATIENTS UNDERGOING COMPLEX ORAL REHABILITATION TREATMENT

Abstract

Chronic apical periodontitis (CAP) is considered to be a dynamic defence response against micro-organisms invasion into periradicular tissues, resulting in a destruction of surrounding periapical bone . Among other important regulatory functions, vitamin D demonstrated to have a role in modulating the inflammatory process of periradicular tissues, in calcium and bone homeostasis and apoptosis. This retrospective study aimed to assess the relationship between vitamin D (VitD) levels and the incidence of large periapical rarefactions in dental patients that further undergo complex prosthetic rehabilitation. In this regard, a number of 28 patients, 54,8% men (n=16) and 45,2% women (n=12) with a complete medical and dental history, in the age range of 18–50 years were taken under observation. They were examined radiographically and clinically to diagnose the presence of CAP, presence and quality of root canal fillings, quality of restoration and periapical status. Another group of 28 patients in the same age range and gender-matched individuals without any history of systemic disease or presence of CAP lesions were included in the study as the control group. Serum VitD levels were analyzed for all patients. The prevalence of teeth with large chronic periapical lesions was 85,7% in the analyzed group The results showed significantly different values of Vitamin D levels in individuals with CAP compared with control patients (P =0,003). The presence or absence of root canal fillings in affected teeth didn’t correlate with the lesion dimension or severity of the evolution.

Keywords

• chronic apical periodontitis (cap)
• vitamin d
• root canal filling
• complex oral rehabilitation