Nature Communications (Oct 2018)

Mass spectrometry and Monte Carlo method mapping of nanoparticle ligand shell morphology

  • Zhi Luo,
  • Yanfei Zhao,
  • Tamim Darwish,
  • Yue Wang,
  • Jing Hou,
  • Francesco Stellacci

DOI
https://doi.org/10.1038/s41467-018-06939-y
Journal volume & issue
Vol. 9, no. 1
pp. 1 – 9

Abstract

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Determining the arrangement of ligands on a nanoparticle is challenging, given the limitations of existing characterization tools. Here, the authors describe an accessible method for resolving ligand shell morphology that uses simple MALDI-TOF mass spectrometry measurements in conjunction with an open-access Monte Carlo fitting program.