Primary pulmonary lymphoepithelioma‐like carcinoma treated with immunotherapy: A case report and literature review

Anita Archwamety; Ruchira Ruangchira‐urai; Charuwan Akewanlop; Krittiya Korphaisarn

doi:10.1111/1759-7714.14580

Thoracic Cancer (Sep 2022)

Primary pulmonary lymphoepithelioma‐like carcinoma treated with immunotherapy: A case report and literature review

Anita Archwamety,
Ruchira Ruangchira‐urai,
Charuwan Akewanlop,
Krittiya Korphaisarn

Affiliations

Anita Archwamety: Division of Medical Oncology, Department of Medicine, Faculty of Medicine Siriraj Hospital Mahidol University Bangkok Thailand
Ruchira Ruangchira‐urai: Department of Pathology, Faculty of Medicine Siriraj Hospital Mahidol University Bangkok Thailand
Charuwan Akewanlop: Division of Medical Oncology, Department of Medicine, Faculty of Medicine Siriraj Hospital Mahidol University Bangkok Thailand
Krittiya Korphaisarn: Division of Medical Oncology, Department of Medicine, Faculty of Medicine Siriraj Hospital Mahidol University Bangkok Thailand

DOI: https://doi.org/10.1111/1759-7714.14580
Journal volume & issue: Vol. 13, no. 17
pp. 2539 – 2541

Abstract

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Abstract Here, we report a case of metastatic Epstein–Barr virus (EBV)‐related primary pulmonary lymphoepithelioma‐like carcinoma (PPLELC) in a young, nonsmoking female who responded well to treatment with two types of immune checkpoint inhibitors (ICIs). This is the first case report of a favorable outcome to ICIs in the late‐line treatment of advanced PPLELC patients with programmed cell death‐ligand 1 (PD‐L1) expression.

Published in Thoracic Cancer

ISSN: 1759-7706 (Print); 1759-7714 (Online)
Publisher: Wiley
Country of publisher: United Kingdom
LCC subjects: Medicine: Internal medicine: Neoplasms. Tumors. Oncology. Including cancer and carcinogens
Website: https://onlinelibrary.wiley.com/journal/17597714

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