Nature Communications (May 2018)

Oxygen and Pt(II) self-generating conjugate for synergistic photo-chemo therapy of hypoxic tumor

  • Shuting Xu,
  • Xinyuan Zhu,
  • Chuan Zhang,
  • Wei Huang,
  • Yongfeng Zhou,
  • Deyue Yan

DOI
https://doi.org/10.1038/s41467-018-04318-1
Journal volume & issue
Vol. 9, no. 1
pp. 1 – 9

Abstract

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Photodynamic therapy has attracted interest in treating cancer but it is limited in hypoxic tumors due to a lack of oxygen. Here, the authors describe a nano-composite capable of generating oxygen under near-infrared light for improved photodynamic and chemotherapy for treating cancer.